The odontogenic fibroma of is a rare benign neoplasm representing 1%2. History indicates that a variety of conditions had been reported as odontogenic fibroma. The tumour developed in the alveolar process of the maxilla in the area of 15. Reactive bone formation involves the lesion haematoxylin and eosin he staining, 40x original magnification. Central odontogenic fibroma cof is a rare tumor that accounts for 0. Central odontogenic fibroma of the maxilla a case report revista. Send orders of reprints at email protected 280 the open dentistry journal, 2014, 8, 280288 open access central odontogenic fibroma of the gingiva. The central odontogenic fibroma is a rare benign odontogenic tumor. Central odontogenic fibroma cof is a relatively rare benign odontogenic neoplasm of jawbones. Central odontogenic fibroma is a rare odontogenic neoplasm that originates from odontogenic ectomesenchyme. Central odontogenic fibroma cof is a rare, benign, slowgrowing.
For many years there was considerable confusion concerning the criteria by which the lesion should be diagnosed and as a result, a verity of different conditions were being reported as odontogenic fibroma of. At a very early stage of the tumour growth which are small, well demarcated and clinically. An odontogenic tumor is a neoplasm of the cells or tissues that initiate odontogenic processes examples include. Cirugia bucal oral surgery central odontogenic fibroma central odontogenic fibroma. Central odontogenic fibroma of the maxilla europe pmc.
It is a lesion associated with the crown of an unerupted tooth resembling dentigerous cyst. Odontogenic fibroma of, a rare odontogenic tumor of mesodermal origin, has been thought to originate from either dental follicle, periodontal ligament, or dental papilla 1. Odontogenic fibroma is a rare tumour of odontogenic mesenchymal origin, which accounts for only 0. It is generally believed that peripheral odontogenic fibroma originates from mesenchymal tissue 9. Odontogenic fibroma of is a rare benign odontogenic neoplasm. Peripheral odontogenic fibroma is the rare peripheral counterpart of central odontogenic fibroma.
Some tumors are true neoplasms, while some are hamartomas developmental malformations. The central odontogenic fibroma cof, as the name implies, is a benign odontogenic neoplasm that occurs exclusively in the. Central odontogenic fibroma a report of a quiet and. Odontogenic fibroma, including amyloid and ossifying variants. The study also presents a oneyear period of postsurgical observation. A case report ugo covani 1, roberto crespi 2, nicola perrini 3, antonio barone 2 1 associate professor and chairman of oral pathology and medicine school of dental medicine and nanoworld institute university of genova, italy. This study evaluated the literature concerning the surgical management of odontogenic myxoma, and reports the longterm outcome of a. This study evaluated the literature concerning the surgical management of odontogenic myxoma, and reports the longterm outcome of a case managed. Cemento ossifying fibroma is a benign, non odontogenic tumour of the jaw, a subdivision of. In their study of fortyfive cases at, the mayo clinic, zimmerman and dahlin12 grouped all of the myxomatous tumors of the jaws together. It is considered to have both epithelial and mesenchymal elements, but it lacks any.
Bernier1 thought that the odontogenic fibroma and the odontogenic myxoma were essentially similar, varying only in maturity the myxoma being the more embryonic form. Odontogenic myxoma is a benign odontogenic tumor with locally aggressive behavior, and is relatively rare in the oral cavity. Peripheral odontogenic fibroma is a benign tumour that arises from the periodontal ligament. Concurrent central odontogenic fibroma who type and. Odontogenic fibroma definition of odontogenic fibroma by. An odontogenic fibroma is a rare benign central tumor of the jaw. Biomedical research journal odontogenic fibroma of maxilla. Central odontogenic fibroma cof is an uncommon benign neoplasm composed by varying amounts of inactivelooking odontogenic epithelium embedded in a neoplastic mature and fibrous stroma 112. Pdf odontogenic fibroma odf is a rare odontogenic tumor. Jul, 2011 odontogenic fibroma, including amyloid and ossifying variants odontogenic fibroma, including amyloid and ossifying variants eversole, lewis 201107 00. This tumor is composed of mature connective tissue which arises from either the embryonic tissue of the dental papilla or the dental follicle. Amaryl lids to download pdf you need some things, like my website and the name of the file.
It has a diverse histopathology and a certain degree of controversy still exists regarding the diagnostic criteria. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader. Here, a case of central odontogenic fibroma in a 17yearold male is reported. Odontogenic fibroma pdf the odontogenic fibroma is a rare, object oriented systems development ali bahrami free pdf dow benign tumor of mesodermal origin, and one of the most illdefined and least understood of all odontogenic neoplasms. The lesion may evolve from a dental germ dental papilla or follicle or from the periodontal membrane, and therefore is invariably be related to the. Oral surg oral med oral pathol oral radiol endod 2004. Ithe present study outlines the case of a 30yearold patient with central odontogenic fibroma. In this paper, we present a case of an uncommon and slowgrowing tumor known as a central odontogenic fibroma cof. It appears as an asymptomatic expansion of the cortical plate of the mandible or maxilla. This is a temporary file and hence do not link it from a website, instead link the url of this page if you wish to link the pdf file. To download the pdf, click the download link below. Peripheral odontogenic fibroma has been reported in all age groups age range.
Alternatively, you can also download the pdf file directly to your computer, from where it can be opened using a pdf reader. Ameloblastic fibroma, is a mixed odontogenic tumor, which commonly affects young children under the age of 20 years, with the mandibular premolarmolar. It can be further divided into peripheral odontogenic fibroma podf and central. They present as firm, smooth swellings of the gingiva and are normally indistinguishable from gingival hyperplasia. Peripheral odontogenic fibroma is an uncommon benign tumour of the gum and is the equivalent of a central odontogenic fibroma occuring outside of bone. Odontogenic fibrosarcoma definition of odontogenic.
Odontogenic tumors comprise a complex group of lesions with varied histopathological and clinical features. Pdf central odontogenic fibroma cof is an uncommon tumor that. Odontogenic fibroma, including amyloid and ossifying variants odontogenic fibroma, including amyloid and ossifying variants eversole, lewis 201107 00. Pdf central odontogenic fibroma of the maxilla researchgate. Different studies reported high variability in the incidence rate as being between 3 and 23% of all odontogenic tumors 2,3. An ameloblastic fibroma is a fibroma of the ameloblastic tissue, that is, an odontogenic tumor arising from the enamel organ or dental lamina. Radiologically it presents as a unilocular or multilocular radiolucency. Odontogenic, tumors, fibroma, central introduction odontogenic fibroma odonf is a mesenchymal odontogenic tumor 1. Benign lesions, central odontogenic fibroma, histopathology, periodontal pathology. The remaining 40% arise from the reduced enamel epithelium of the dental follicle and are thus dentigerousorigin odontogenic keratocysts figure 7 b as we. Here we report four types of odontogenic tumor including six cases in which five had mutation according to next generation sequencing analysis from archival paraffin blocks that diagnosed previously as ameloblastoma solid, amloblastoma unicysticmural, ameloblastic fibroma, squamous odontogenic tumor, and adenomatoid. Most odontogenic keratocyst 60% arise from dental lamina rests or from the basal cells of oral epithelium and are thus primordialorigin odontogenic keratocysts figure 7a 10. A clinicopathological study of 15 cases article pdf available in journal of the formosan medical association 1101. Central odontogenic fibroma cof is an extremely rare benign tumor that accounts for 0.
Central odontogenic fibroma of the maxilla a case report. Clinically, of is most common in the mandibularpremolar region of female patients in the second to fourth decades of life and is frequently found as radiolucent lesions that may induce root resorption. The who defines central odontogenic fibroma as fibroblastic neoplasm containing variable amounts of apparently inactive odontogenic epithelium and is classified as odontogenic tumor of ectomesenchyme with or without. Central odontogenic fibroma of maxilla a case report. A case report ahmad soolari and asghar khan university of maryland dental school, baltimore, md, usa abstract. Odontogenic fibroma odf is a rare odontogenic tumor. This is a pdf file of an unedited manuscript that has been accepted for publication. Consists of variably cellular fibrocollagenous tissue with scattered, small, inactive odontogenic epithelium in strands, cords or nests calcification can be seen in association with odontogenic epithelium and when extensive could consider classification as ossifying variant of odontogenic fibroma. Some are composed only of odontogenic epithelium, while many are mixed i. Since the present case showed a multilocular radiolucency with partially illdefined border between the right mandibular condyle and the distal root of the. Central odontogenic fibroma is a benign odontogenic tumor derived from the dental ectomesenchymal tissues. Molecular profiling of odontogenic tumors pilot study in. Odontogenic fibroma of, a rare odontogenic tumor of mesodermal origin, has been thought to originate from either. In this report, a 10yearold male patient is presented, who was diagnosed with central odontogenic fibroma of simple type from clinical, radiological, and histopathological findings.
A novel cause of cherubism, journal of oral and maxillofacial surgery 2014, doi. Odontogenic tumors fibroma adult humans pathology diagnosis a b s t r a c t central odontogenic. Central odontogenic fibroma cof is a rare, benign neoplasm of mesenchymal origin that makes up less than 5% of odontogenic tumors commonly found in women in ratio 2. This rare case of cof, which was documented over a period of 20 years, has helped us to describe the features of this tumor. Large mandibular central odontogenic fibroma documented over 20. The lesion appears both in the maxilla and mandible. Kleiber gm, skapek sx, lingen m, reid rr, odontogenic myxoma. It is usually found either in the anterior maxilla or the posterior mandible. Aarthinisha sree balaji dental college and hospital, bharath university, chennai, india abstract. Epithelium rich type central odontogenic fibroma in maxilla. It may evolve from the dental follicle, the dental papilla, or the periodontal membrane. A central odontogenic fibroma cof is a rare tumor of odontogenic origin with a diverse histopathology found in both the mandible and the maxilla. It must be distinguished from the more common peripheral ossifying fibroma.
It is a rare lesion that could be seen in all agegroups and that it is found both in the mandible and in the maxilla. It was previously known as a fibromatous epulis and ossifying epulis depending on the degree of mineralization. There are currently no clear surgical management guidelines for odontogenic myxoma, and a variety of approaches may be used. Odontogenic fibroma, central ddmfr oral and maxillofacial. Here, a case of central odontogenic fibroma of the mandible in a 71yearold man is described. A central odontogenic fibroma cof is a rare and benign tumor accounting for only 0. Dec 01, 2015 odontogenic fibroma of, a rare odontogenic tumor of mesodermal origin, has been thought to originate from either dental follicle, periodontal ligament, or dental papilla 1. Aug, 2010 central odontogenic fibroma cof is an uncommon benign neoplasm composed by varying amounts of inactivelooking odontogenic epithelium embedded in a neoplastic mature and fibrous stroma 112. Odontogenic fibroma pdf odontogenic fibroma pdf odontogenic fibroma pdf download. The ameloblastic fibroma is an odontogenic tumour with an unusual presentation. Hara m, matsuzaki h, katase n, yanagi y, unetsubo t, asaumi j, et al. A case of odontogenic fibroma, a slowly growing, uniloculated cystic cavity with a thinned but intact outer cortex of the mandible in a female patient aged 26 years, is reported in the light of the available literature.